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KMID : 1146620230120010001
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Journal of Korean Academy of Advanced General Dentistry
2023 Volume.12 No. 1 p.1 ~ p.7
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Tooth Loss and Long-term Clinical Outcomes in Kidney Transplantation Recipients
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Heo Hyun-A
Park Su-Hyun
Yoon Hyun-Joong
Pyo Sung-Woon
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Abstract
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Tooth loss is considered as a representative index of poor oral health. The aim of this study was to identify clinical outcomes following kidney transplantation in relation with the number of tooth loss. Clinical data from 978 patients receiving kidney transplantation between 2010 and 2020 in a single cohort was investigated. Groups were divided according to number of tooth loss (0 to 4, 5 to 9, over 10). Retrospective study was performed by univariate and multivariate logistic statistical analysis for association of clinical variables, recipient’s kidney function, acute rejection episode after kidney transplantation and death with the number of tooth loss. The age, gender, body mass index, accompanying comorbidities, preoperative laboratory values and immunosuppressive regimens were not related with the number of tooth group. No significant association was found between the number of tooth loss and kidney function and risk of rejection after kidney transplantation. However, tooth loss was positively associated with patient survival who had more than 10 teeth lost (HR 26.268, 95% CI 3.506-196.82, P<0.001). There was no direct evidence that poor oral health could worsen the clinical outcome of kidney transplantation. However, the status of tooth loss might jeopardize the survival of kidney transplantation recipients. The participation of oral health care providers in the transplantation team is recommended.
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KEYWORD
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Oral health, Tooth loss, Chronic kidney disease, Transplantation, Clinical data
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